Reflections on AIDS 2022 from a DSD perspective. The current state of differentiated service delivery (DSD) and innovative DSD strategies to enhance HIV treatment, integration, pre-exposure prophylaxis (PrEP)
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Welcome to the third differentiated service delivery (DSD) newsletter of 2022 from IAS – the International AIDS Society. In this edition, we focus on the DSD science presented at AIDS 2022, the 24th International AIDS Conference. 

Reflections on AIDS 2022 from a DSD perspective

Nittaya Phanuphak, Executive Director at the Institute of HIV Research and Innovation in Bangkok, Thailand, writes:  


The current state of differentiated service delivery (DSD) and innovative DSD strategies to enhance HIV treatment, integration, pre-exposure prophylaxis (PrEP) and testing service delivery were discussed extensively at AIDS 2022, held in person in Montreal, Canada, and virtually, from 29 July to 2 August.


Acknowledging that a growing number of people living with HIV may have periods of treatment interruption, the IAS-organized pre-conference meeting, “Differentiated service delivery for HIV treatment in 2022”, dedicated one of its sessions to highlighting the role of DSD in supporting sustained re-engagement. Differentiation at re-engagement was shown to be an area where more work will be necessary in the coming years.

The World Health Organization’s technical brief with implementation guidance for simplified and DSD for PrEP, launched during AIDS 2022, removes the need to obtain creatinine and hepatitis serology test results before PrEP initiation. This will likely enable many more DSD models to explore offering more PrEP service delivery options for clients. The global goal to reach 3 million people with PrEP by 2020 was missed and the new goal is to reach 10 million people with PrEP by 2025. Therefore, we need to significantly scale up PrEP roll out in order to end the HIV epidemic. DSD is a key guiding principle for achieving that goal.


Read the full piece

 

DSD in action: Integrating hypertension services in DSD models in Malawi

"One of the big lessons from our work on integration of HIV treatment and hypertension is that people really like MMD and it was clear that the strategy does address some of the socioeconomic barriers at an individual level."

We spoke with Khumbo Nyirenda who works as Senior Implementation Science Manager at Partners in Hope (PIH) in Lilongwe, Malawi.

What are the key components of the PIH service delivery model to integrate hypertension services within DSD for HIV treatment models in Malawi?


PIH implements a wide range of DSD models for HIV treatment, including multi-month dispensing (MMD), using up to six-month MMD and community ART distribution. These DSD models have been proven to reduce the risk of disengagement from care and also reduce the cost of care to an individual. Formative work from our group showed that people living with HIV and hypertension do experience these barriers as well, but did not have access to DSD models.

What are the key lessons learnt from implementing the PIH project on hypertension integration within DSD in Malawi?


One of the big lessons from our work on integration of HIV treatment and hypertension is that people really like MMD and it was clear that the strategy does address some of the socioeconomic barriers at an individual level. However, despite MMD and alignment of ART and hypertension medications, blood pressure control levels are still quite low, suggesting that we do need additional interventions to be able to positively influence clinical outcomes like blood pressure control.

At a policy level, what needs to be done to support integration of NCDs into DSD for HIV treatment models? 


We need more evidence that integration of HIV treatment and non-communicable diseases (NCDs), especially hypertension, works for the health facilities and systems in terms of supply of commodities and also showcasing evidence that people do really want and appreciate DSD models that integrate MMD and medication alignment for hypertension. More research around other interventions that can influence clinical outcomes, like blood pressure control, would facilitate decision making at the policy level.

Read the full interview

 

Don't miss

DSD Science at AIDS 2022

Check out the AIDS 2022 DSD science slide deck and discover the latest DSD science. 

 

Looking ahead, looking back

Looking ahead …

  • 30 September: This is the submission deadline of the call for abstracts for a new Journal of the International AIDS Society (JIAS) special issue, titled “Understanding challenges and optimizing outcomes of children with perinatal HIV exposure”, to be published in conjunction with the International Paediatric HIV Symposium in Africa (IPHASA) in November 2023. 
  • 5-6 October: Virology Education is convening the International Workshop on HIV & Adolescence 2022 in Cape Town, South Africa. 
  • 21 October: The focus of the fifth meeting of the South African Measurement and Surveillance of HIV Epidemics (MeSH) team will be on differentiated service delivery and aims to foster further collaboration and strengthening of routine HIV information systems in South Africa. Register for the virtual meeting here. You can view previous sessions on the MeSH YouTube channel.
  • 21-23 November: Register for the hybrid 2022 PATA Summit titled “Ending AIDS in Children, Adolescents and Young People – a Roadmap to 2030”.

Looking back …

  • 21 September: The seventh replenishment of the Global Fund took place in New York, United States, with Global Fund partners pledging USD 14.25 billion, falling short of the USD 18 billion target. The UK and Italy are still to pledge in the coming weeks.
  • 15-19 August: The HIV Coverage, Quality, and Impact Network (CQUIN) held a meeting, titled “Differentiated Service Delivery Across the HIV Cascade: Leveraging DSD Strategies to Optimize Linkage, Retention, and Re-engagement”, in Kigali, Rwanda.
  • 9 August: Watch the recording of the webinar, “Bringing ART Closer to Communities: The Role of Community Pharmacy DSD Models”, organized by CQUIN.
  • 29 July-2 August: AIDS 2022 took place in person in Montreal and virtually. Find the full conference programme here and learn more about the IAS-organized DSD pre-conference meeting on re-engagement and satellite sessions on DSD science and PrEP here. Session recordings are available on demand to registered delegates and from 4 October to the public.
  • 27 July: WHO published the technical brief, “Differentiated and simplified pre-exposure prophylaxis for HIV prevention: update to WHO implementation guidance”. The brief aims to support a range of stakeholders in planning and implementing PrEP services and supplements, and updates previously published WHO PrEP implementation guidance. To support countries in developing a DSD for PrEP policy, IAS developed this country policy development brief.

 

What we're reading

Adolescent retention in HIV care within differentiated service-delivery models in sub-Saharan Africa, Maskew M et al, Lancet HIV, September 2022


This review of differentiated service delivery models in an adolescent context found that few differentiated models of care specifically targeted at adolescents existed and adolescents were ineligible for several models that exist. The authors conclude that future programme design should be guided by adolescents and supported by robust research.


Experiences of participants in a decentralized antiretroviral therapy program in South Africa during the COVID-19 pandemic, Jarolimova J et al, AIDS Care, July 2022


Using semi-structured phone interviews, this qualitative study sought to evaluate experiences of people receiving ART through a decentralized delivery programme in South Africa during the first months of the COVID-19 pandemic. Participants who were enrolled in the decentralized ART programme for more than 12 months were less concerned about infection risk associated with ART pickup. 


Adequate funding of comprehensive community-based programs for key populations needed now more than ever to reach and sustain HIV targets, DiCarlo M et al, JIAS, July 2022


This commentary calls for investments in community-based and community-driven key population programmes that address structural inequities. The authors warn that inadequate funding for key population programmes will prevent the global community from reaching the 95-95-95 targets. 


Client and healthcare worker experiences
with differentiated HIV treatment models in Eswatini
, Reidy W et al, PLOS One, May 2022


This mixed-methods study explored client and
healthcare worker perceptions of differentiated ART models in Eswatini. The most common models were fast-track, outreach and community ART groups. A high majority of clients reported that they were very satisfied with their care.


Patient experiences and preferences
for antiretroviral therapy service provision:
implications for differentiated service delivery in Northwest Ethiopia
, Belay YA et al, AIDS Research and Therapy, June 2022


Conducted as part of a larger discrete choice experiment, this qualitative study explored client experiences of taking ART and preferences for ART service delivery. The preferences of participants toward most ART service delivery features were heterogeneous, but the majority preferred the frequency of six-month ART refill visits and facility-based over community-based services. 


Availability and experiences of differentiated antiretroviral therapy delivery at HIV care facilities in rural Zimbabwe: a mixed-method study, Christ B et al, JIAS, August 2022


This cross-sectional mixed methods study assessed the availability, experiences and perceptions of differentiated ART delivery in HIV care facilities in a rural district in Zimbabwe. While differentiated ART delivery models were widely available, most facilities did not offer a choice of models to address clients’ diverse preferences.


Assessment of a viral load result-triggered automated differentiated service delivery model for people taking ART in Lesotho (the VITAL study): Study protocol of a cluster-randomized trial, Tschumi N et al, PLOS One, May 2022


This study protocol describes the cluster-randomized trial to assess a viral load result-triggered automated differentiated service delivery model (VITAL model) for adults taking ART in Lesotho. The objective is to determine if the VITAL model is at least non-inferior to the standard of care with viral suppression at 24 months’ follow up and if it saves costs.


 

What we're watching

How to write and submit a research manuscript: Publish or Perish


In this webinar, organized by the IAS Educational Fund, Journal of the International AIDS Society Executive Editor Marlène Bras and Deputy Editor Anna Grimsrud describe the main parts of a scientific article and the modalities of publication, the process of peer review and the main reasons for article rejection.

The webinar aims to build skills in scientific writing and provides practical information to support new- and early-career HIV researchers, as well as more experienced researchers, in successfully submitting their manuscripts to peer-reviewed journals.

 

Get in touch

Do you have content for the next newsletter? We want to hear from you. Email us at dsd@iasociety.org.


www.differentiatedservicedelivery.org

 

Photo credits in order of appearance: 
(1-3) IAS

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